Boss Kieran McKenna made four changes with skipper Sam Morsy coming back into his usual central midfield role for Lee Evans, who was absent from the 20-man squad having suffered a knee injury at Huddersfield on Saturday.
Brandon Williams took over from Harry Clarke at right-back with the former Arsenal man dropping to the bench.
George Edmundson’s first league start of the season came for Cameron Burgess, who was missing from the squad, presumably having picked up a knock.
Marcus Harness was on the left of the trio behind the striker with Omari Hutchinson, starter on Saturday and against Wolves last Tuesday, among the subs.
Also on the bench was Christian Walton, for the first time in the league since joining Town in the summer of 2021, returning to the squad for the first time this campaign having suffered a plantar fascia injury in pre-season, along with Nathan Broadhead, who missed the trip to the John Smith’s Stadium with a minor thigh problem.
Hull, who had won their last six at Portman Road and were unbeaten in seven on Suffolk soil, made three changes from the team which drew 1-1 with Plymouth Argyle at the weekend.
Lewie Coyle came in for Ruben Vinagre and Jacob Greaves for Sean McLoughlin with the two men out of the XI on the bench, while Liam Delap took over from Regan Slater, who is out with a hamstring injury.
Town, with sponsor Ed Sheeran watching from his box having appeared on Town TV and behind one of the Portman Road bars prior to kick-off, took the lead via the game’s first serious attack in the fifth minute.